Harvard University Graduate School of Design professor and alumnus Hashim Sarkis has been appointed as Dean of the MIT School of Architecture and Planning.Sarkis is currently the Aga Khan Professor of Landscape Architecture and Urbanism in Muslim Societies at the GSD, and has been on the faculty since 1998. The Aga Khan Program is a joint endeavor between Harvard and MIT, and is a leading program for the study of architecture, urban issues, and visual culture in Islamic societies.In addition to his teaching and writing, Sarkis is the founder and principle of Cambridge- and Beirut-based Hashim Sarkis Studios, which has won numerous competitions and designed civic and commercial projects, as well as private houses, from Massachusetts to Lebanon and the United Arab Emirates.Sarkis received his BArch and BFA from the Rhode Island School of Design in 1987, his MArch from the GSD in 1989, and his PhD in architecture from the GSD in 1995. Read Full Story
Jun 10, 2004 (CIDRAP News) The US Postal Service (USPS) has begun installing anthrax-detection systems in major mail-processing centers and hopes to have the equipment in 100 facilities by the end of this year. After testing the Biohazard Detection System (BDS) for nearly 2 years in Baltimore, the USPS began installing the system in major processing and distribution centers in March, said Bob Anderson, a USPS spokesman in Washington, DC. See also: The detection system includes an air-collection hood over machines that handle “raw” mail collected from mailboxes, Anderson said. Air samples are drawn to a cabinet where they are tested automatically for anthrax. The system can be expanded to test for other pathogens, but currently it only tests for anthrax, he said. Besides testing the system initially in Baltimore, the Postal Service ran one-month tests of the equipment at 14 facilities last summer, Anderson said. The equipment was removed from those plants after the tests. “Equipment has been installed and I believe it’s up and running in six of those facilities,” Anderson told CIDRAP News. “I believe the equipment is arriving at the seventh tomorrow.” He said installation of the system is moving generally from east to west, with Pittsburgh and Cleveland among the first cities to get the equipment. He said no evidence of anthrax has been detected by any of the systems so far. He said plans call for installing the system in about 100 facilities by the end of November of this year and completing the project with another 183 installations in 2005. Northrop-Grumman, primary contractor for the project, is doing this year’s work under a $175 million contract, he said. The amount for next year’s work has not yet been determined. USPS news releases (click on Jun 4 release, “Biohazard Detection System Deployment Resumes”)http://www.usps.com/communications/news/press/welcome.htm USPS officials are meeting with local and state health officials in each city before the equipment is installed, Anderson said. “We have to meet with those officials and first responders and work out an emergency response plan in case we do detect anthrax in the mail,” he said. The inconclusive results “meant that a small, but unacceptable, number of tests had to be rerun to obtain conclusive results,” Azeezaly S. Jaffer, USPS vice president for public affairs, said in the news release. “Had anthrax been present, it would have been detected by the BDS. BDS has proven that it consistently and reliably detects anthrax in the mail.” The USPS decided to add the equipment after the anthrax-by-mail attacks in the fall of 2001. The attacks killed five people, including two postal workers, and caused 17 other cases of illness. The installation begun in March was suspended Apr 28 for testing to find out why some systems were yielding “inconclusive” results, the USPS reported. The project resumed Jun 4 after the problems were identified and corrected, the agency said in a news release.
Don’t miss out on the latest news and information. Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award NBA teams paying closer attention to players’ wingspan LATEST STORIES Scientists seek rare species survivors amid Australia flames Jo Koy draws ire for cutting through Cebu City traffic with ‘wang-wang’ Simmons is averaging 16 points a game in his rookie season, a huge reason for Philadelphia’s success after years of rebuilding. The 76ers need to win their final two games to lock up the third seed in the Eastern Conference.FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkSPORTSTim Cone, Ginebra set their sights on elusive All-Filipino crown P16.5-M worth of aid provided for Taal Volcano eruption victims — NDRRMC Green group flags ‘overkill’ use of plastic banderitas in Manila Sto. Niño feast Jiro Manio arrested for stabbing man in Marikina Nadine Lustre’s phone stolen in Brazil MOST READ Judy Ann’s 1st project for 2020 is giving her a ‘stomachache’ Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew Truck driver killed in Davao del Sur road accident Philadelphia 76ers’ Ben Simmons, left, of Australia, shoots during the second half of an NBA basketball game against the Dallas Mavericks, Sunday, April 8, 2018, in Philadelphia. The 76ers won 109-97. (AP Photo/Chris Szagola)ATLANTA — Ben Simmons is playing for the streaking Philadelphia 76ers in their next-to-last game of the regular season after missing the morning shootaround because of an illness.Simmons was listed as questionable for the game in Atlanta against the Hawks after being diagnosed with stomach flu. But coach Brett Brown says Simmons is feeling well enough to play with the 76ers attempting to set a franchise record with their 15th straight win.ADVERTISEMENT Sports Related Videospowered by AdSparcRead Next View comments
Letterkenny businesses owners and staff are being advised to be on alert for fake bank notes from Northern Ireland.The alert was sparked by the attempted use of a fake £50 sterling note in a local business on Tuesday night.According to the Letterkenny Chamber, staff identified the note was a forgery and the person left in a hurry. Staff are advised to take care to check all notes and report any incidents to gardaí.Warning issued over fake sterling notes in circulation was last modified: March 19th, 2019 by Rachel McLaughlinShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:bank notesLetterkenny Chamber
Cells are like castles surrounded by walls. A wall without gates, however, would prevent commerce and trap the inhabitants inside. The cell has ingenious gates that control the flow of goods and services through its outer membrane under tight surveillance and quality control. This controlled flow, as opposed to passive diffusion or osmosis, is termed active transport. Depending on the type of import or export required, the cell uses a variety of mechanisms. It might wrap the cargo in clathrin proteins and send it through in a self-mending breach of the walls (endocytosis; 05/15/2005, 11/04/2005, bullet 7). It might use one of the specialized authenticating channels through the membrane (e.g., aquaporins 04/18/2002 and ion channels, 05/29/2002). It might export genetic material or proteins through one of the pumps, or secretion systems (10/11/2005, 11/10/2004). Or, it might check cargo through one of the varieties of self-operating ticketed turnstiles. A description of one of these gates excited awe in a commentary in PNAS.1 Robert M. Stroud summarized decades of work on a kind of lactose turnstile. Key researchers published their latest results in the current issue of the journal. They believe they have finally figured out how this molecule-sized machine works. It is a protein, 417 amino acids long, folded into a kind of rocking door in the membrane. For a lactose passenger to get through the membrane using this transporter, it has to pay the fare: a proton ticket must first be inserted into the active site. Then, the lactose molecule gets in and fastens its seat belt, so to speak, for the short but wild ride. The nanomachine undergoes a conformational change that seals off the outside and opens the door to the inside, where the passengers undock. Then, the gate automatically repositions itself for the next load. Called LacY, or lactose permease, this molecular machine operates with practically 100% efficiency: each proton ticket grants admittance to one and only one lactose passenger. LacY is one of a whole family of gates called the “Major Facilitator Superfamily” (MFS).2 “The mechanism most probably pertains to the many other transporters of the MFS that are found throughout all domains of life,” Stroud says. Another member of this family, for instance, is called GlpT. This machine works with a reverse-ticketing process; a phosphate outside the cell is exchanged for a glycerol phosphate inside. Stroud was palpably delighted with the elucidation of the mechanism of these intriguing nanomachines after so much research by so many scientists for so many years. Here’s what he said about the LacY device:The MFS of transporters can be run in reverse, such that outward movement of lactose, driven by reverse concentration gradient, can generate an H+ gradient across the membrane; LacY can work in either direction toward a coupled equilibrium. It is a beautiful example of energy transduction at the level of the membrane and is a near-perfect machine in the sense that the stoichiometry3 is always 1:1 without any leakage.Leakage would allow contraband through. Experimental inventory shows all goods accounted for, before and after. The protein undergoes “large global conformational changes to transport the cargo” that are reversible, providing “oscillation between structural states that become accessible alternately to one side or the other, which can therefore be coupled to other sources of energy.” Understanding how these machines work could lead to treatments for diseases, such as cystic fibrosis and lactose malabsorption, caused by malfunction of the gates. In addition, medical researchers may discover novel ways to co-opt the gates for special delivery of antibiotics and chemotherapeutic drugs.1Robert M. Stroud, “Transmembrane transporters: An open and closed case,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0610349104, published online before print January 24, 2007.2Another superfamily of transporters, the ATP Binding Cassette (ABC) family, is driven by ATP hydrolysis inside the cell.2Stoichiometry refers to the ratios of combining elements in a chemical reaction, from the Greek stoichea, “basic principles,” as used in Colossians 2:8.Wonderful, amazing, mind-boggling discoveries come from the investigation of design in nature. Stroud said nothing about how these machines arose by evolution; indeed, he said these mechanisms are “found throughout all domains of life.” Moreover, this particular 100%-efficient machine is made up of 417 amino acids. Our online book calculates the probability for a 400-amino-acid protein arising by chance as one in 10161. This unfathomably low probability rules out its formation by any lucky accident in trillions upon trillions of universes (ch. 7). The LacY protein machine cannot tolerate much error, either. One primary method the scientists use to learn about them is by replacing amino acids with the wrong ones, and watching how the machines break. From the top of the giraffe to the lowly crocus, molecular machines transduce life within a physical medium. This is no hocus, folkus. This is intelligent design coming into focus – at the locus of mind and matter, at the intersection of faith and reason. Let the NCSE run for cover, wailing, “Cloak us from the face of ID, for the facts emerging from biophysics provoke us to shame and despair.” Rejoice, O science, as the lens of molecular biology leads to a refocus on intelligent design.(Visited 30 times, 1 visits today)FacebookTwitterPinterestSave分享0
The International Marketing Council of South Africa (IMC) has embarked on an ambitious campaign to raise awareness about the country in the British capital.The campaign is an extension of last year’s branding exercise, which saw ten taxis branded with the “South Africa: Alive with Possibility” logos and each given mind-opening headlines about South Africa. This time around, the ten additional taxis are more colourful and resplendent in colours of the South African flag.London commuters now have a colourful alternative to the traditional black taxis.The sassy vehicles with lively slogans on the side are bound to catch eyes on the streets of London.On the sides of the vehicles are positive messages about South Africa, including – “South Africa: gateway to 800 million opportunities”One of the objectives of the campaign is to redress international perceptions by communicating South African achievements in a compelling manner. Another aim is to persuade people of the world to perceive South Africans as ingenious – always finding new ways of doing things and that they develop new, fresh and practical solutions to their challenges. The messaging on the taxi highlights South African gains in the fields of infrastructure, government stability, economic development, business efficiency and tourism.This campaign is part of a global outreach campaign by the IMC to raise awareness on South Africa’s status as place to do business with. It comes on the back of a successful Branding and Investment Mission to Europe, including London, in June where leading business minds were engaged with South African business leaders on various investment and business initiatives.IMC Marketing Director Kheepe Moremi says: “There has been unprecedented praise for the Alive with Possibility initiative in London. In line with our new corporate identity we have boldly incorporated the beautiful colours of the South African flag, ensuring that we drive the message home in a compelling manner.”IMC Country Manager for the UK John Battersby says: “London is the financial capital of the world. Without a doubt, South Africa is being noticed in London for all the work that is going into sustaining our economic growth and the taxis will enhance our overall efforts into the global thrust.”This is part of the IMC’s initiative of engaging with thought leaders and influencers in different touch points, be it at home — through global television and print campaigns –, or out of home, using taxis, airport advertising and branding missions.Currently, the IMC has campaigns running in The Economist Magazine (advertising), CNBC Europe (vignette) and Heathrow Airport (on the Heathrow Express and the respective platforms).
Share Facebook Twitter Google + LinkedIn Pinterest We make it through most of today dry over a large part of the state. We need to keep watch for some light moisture in NW and far western Ohio today, but rains really do not develop until we get closer to this evening. Thick clouds and well organized arrive in WW Ohio tonight, and then continues to spread across the southern half of the state through the overnight tonight, through tomorrow and then exits early Sunday morning. We are making no changes to this forecast. The moisture is light to moderate, but consistently spread over the period from tonight through tomorrow. We will put coverage at nearly 100% of the state from I-70 southward. The moisture pushes north later in the afternoon tomorrow, particularly over east central Ohio, and then tomorrow night we can see the rains all the way up into NE Ohio. Only NW Ohio misses out on the rain Saturday. We are keeping rain totals at half to 1.5″ south of I-70 with a few localized totals closer to 2″ in SW Ohio, .2″-.6″ from I-70 to US 30, and from a few hundredths to .5″ over the NE quarter of the state. Everything should be pushing off to the east by mid to late morning Sunday. The map at right shows rain totals through Sunday morning.High pressure comes in for Sunday late afternoon and evening. It should give us a quick move back to dry weather. That dry pattern holds through next Wednesday. A second high pressure center moves across the state toward Monday afternoon-Tuesday. Temps will fall off Sunday and Monday, but not by too much, and then we climb again, and should be near normal through a good chunk of the week. Moisture is back for the second half of next week, as scattered showers arrive Thursday morning. At this time, we are expecting a few hundredths to .4” rain potential with coverage at 80% of the state. This will be a relatively light rain event. All action does look to be out of here by Thursday night near midnight. Much colder air starts to funnel in behind the system, and we go dry for that Friday and the following weekend. At this point we look for air to be cold enough for snow for that weekend ahead of Christmas, but we actually do not see any significant snow chances. The extended period remains dry through the 26th. Cold air dominates through that period. We look for south winds to start to develop on the 27th ahead of our next system, which arrives late the 27th into the 28th. This will moisture of .25”-.75” liquid equivalent, but right now we are going to allow for either rain or snow.
zoomImage Courtesy: Pixabay under CC0 Creative Commons license Around 50 percent of the shipment of food to Yemen has been cut as many ships are refusing to dock at the country’s port of Hodeidah due to the escalation of fighting, UN said. As explained, shipping companies appear to be reluctant to call at Hodeidah as they see the insecurity in the port.“Over the last two weeks, the activities have been cut by half. If this continues, it will have a drastic and immediate impact, not only on WFP’s availability to distribute food, but also on prices in local markets,” Stéphane Dujarric, Spokesman for the UN Secretary‑General, said.With the port receiving around 70 percent of imports, a decrease in deliveries of wheat and other supplies would affect food stocks in Yemen, Al Jazeera cited a spokesperson of UN’s World Food Programme (WFP) as saying.The multi-year conflict in Yemen is pushing millions of people to the brink of famine. According to WFP’s data, some 17.8 million Yemenis are food insecure, 8.4 million of which severely so.
SAINT JOHN, N.B. – It’s only been in Saint John for a couple of days, but a Haligonian tugboat is already a big hit in New Brunswick.A replica of the titular main character in the children’s television series “Theodore Tugboat,” Theodore Too will spend the summer in the New Brunswick port city after living in the Halifax harbour for the past 18 years.The beloved tugboat swept into the Saint John harbour on Thursday before a crowd of eager spectators, and will remain there until its departure back to Nova Scotia in October.Miranda McCollum, 29, and her toddler Kyler Daigle-McCollum were part of Theodore’s Saint John welcoming committee.“Even though it was foggy, we sat there and watched him come in the harbour, tooting,” she said in a phone interview Saturday. Kyler “was amazed. He was standing and clapping and cheering.”Like many Atlantic Canadians, McCollum grew up watching “Theodore Tugboat,” which originated in Halifax and chronicled the adventures of Theodore and his friends in the Big Harbour.The tugboat’s much-anticipated visit bodes well for New Brunswick, according to Discover Saint John executive director Victoria Clarke.During a phone interview Saturday, she said Theodore’s affable presence will act as both a tourist attraction and a way to get more locals on the waterfront this summer.“Locals are just absolutely delighted to see his smiling face in our port,” she said, adding that Theodore fans span multiple generations. “Folks that have grown up watching him on TV and have not had the opportunity to see him in Halifax now have a closer-to-home opportunity.”Theodore’s time in New Brunswick will be a mix of work and play: on its work days, the tugboat will host harbour tours and cruise excursions and welcome new ships to the port.It will spend its off time hunkered down at Pugsley Slip, a prominent spot on the Saint John waterfront.Paula Copeland, a spokeswoman with Port Saint John, said the city doesn’t have the variety of boat tours that Halifax does, and that Theodore’s stay will help fill that gap.“We don’t have a lot of water product for tourism,” she said. “And of course, we’re a cruise port, so it’s going to be great for the cruise business to have that availability there.”She added that the boat’s presence alone helps brighten the waterfront.“You can’t not smile when you look at him,” she laughed.Theodore’s arrival in New Brunswick, however, was not without controversy.Ambassatours Gray Line, the company that owns the boat, announced last month that Theodore will spend the summer away from home — much to the annoyance of some Haligonians, who took to social media to accuse the smiling, baseball-cap-clad vessel of treachery.But Ambassatours spokeswoman Terri McCulloch said Halifax has had Theodore for many years, and it’s time someone else gets a turn.“Obviously, the show was set in Halifax and Haligonians have a great affinity for Theodore. He’s definitely been a fixture on the waterfront,” she said.“It caught a few folks by surprise, and certainly, we didn’t mean to offend anyone. He’s still in the region here, so perhaps it’s a nice opportunity for someone to take a little trip over on the ferry (from Digby, N.S.) and pop over to Saint John’s and see how he’s doing over there.”She also pointed out that Theodore has already spent time outside of Halifax, noting it has spent several summers in Quebec and embarked on a 50-city tour along the Eastern seaboard about 10 years ago.On Sunday, Port Saint John is hosting its annual Community Day, which is expected to draw thousands of people to the waterfront to take a gander at the famous boat.
Advertisement Facebook Tenille Arts was born and raised in the small, Canadian prairie town of Weyburn, Saskatchewan. Tenille’s dream of performing took root at the age of 8, when a neighbor overheard her singing a Shania Twain song in her backyard and encouraged her mom to help her pursue music. After years of hard work, Tenille began making the long trip to Nashville to advance her songwriting skills. Her determination and talent lead to steadily increasing success as she earned a publishing deal in Nashville, resulting in her 2016 debut EP, and subsequent 2017 full-length album “Rebel Child”.Tenille inked a recording deal in March 2018 with Reviver Records, resulting in brand new music, including “Mad Crazy Love”.FIND TENILLE ARTS ON SOCIAL MEDIA: Tenille Arts Login/Register With: Advertisement Twitter WEBSITEINSTAGRAM FACEBOOKTWITTER LEAVE A REPLY Cancel replyLog in to leave a comment Advertisement